All of Us Seeks Public Input to Inform Plans for Child Enrollment

All of Us Seeks Public Input to Inform Plans for Child Enrollment

The Child Enrollment Scientific Vision Working Group of the All of Us Advisory Panel seeks public input on the pediatric research that the All of Us Research Program may be uniquely positioned to enable through the enrollment of children.  All responses must be submitted via web form by September 12, 2017, for the working group members to consider during the development of their report. 

Human Genome Editing

Human Genome Editing

Genome editing is a tool used in the laboratory setting to make changes to a organism's genetic material. A recent report from the National Academies of Sciences provides a review of the advances in this technology and offers recommendations for safe use of genome editing to improve human health. Yesterday a new Nature publication about the first human embryo gene editing in the US at OHSU stimulates discussion and controversy about the potential risks for future generations.

New Pediatric Clinical Trial Testing Targeted Drugs for Childhood Cancers

New Pediatric Clinical Trial Testing Targeted Drugs for Childhood Cancers

This targeted treatment study is for children and adolescents (ages 1 to 21) with solid tumors no longer responding to standard treatment or have recurred after treatment. The study matches patients with therapies aimed at molecular abnormalities in their tumors. Enrollment is available at children’s hospitals, university medical centers, and cancer centers across the US that are part of the Children's Oncology Group.

 

Ever wonder why it's so hard to keep that weight off as we age?

Ever wonder why it's so hard to keep that weight off as we age?

NIH Researcher has identified a muscle enzyme in mice, called DNA-PK that increases with age, slowing down the body's metabolism.  This increase may lead directly to weight gain.  Wouldn't it be great to have a magic pill that along with exercise and healthy diet helped us maintain that slim figure?  

 

Legislation proposed that will allow employers to ask about employees’ private genetic information or medical information

Legislation proposed that will allow employers to ask about employees’ private genetic information or medical information

Newly proposed U.S. Legislation threatens to weaken protections provided through the Genetic Information Nondiscrimination Act of 2008.  Preserve the nondiscrimination protections afforded to all Americans by GINA and the ADA by opposing The Preserving Employee Wellness Programs Act, H.R.1313 . 

 

New Gene Variant Linked to Obesity in People of African Descent.

New Gene Variant Linked to Obesity in People of African Descent.

Obesity is a global health problem, contributing to premature death and morbidity by increasing a person's risk of developing diabetes, hypertension, heart disease and some cancers. While obesity mostly results from lifestyle and cultural factors, including excess calorie intake and inadequate levels of physical activity, it has a strong genomic component (NHGRI, 2017)

What is a Chimera?

What is a Chimera?

In Greek mythology, the Chimera was an awesome fire-breathing monster visualized with the head of a lion, the body of a goat, and the tail of a serpent. Today, a medical definition of chimera refers to the possibility to create human-animal chimeras for human organ transplant.

Why aren't high risk patients with breast cancer getting genetic testing?

Why aren't high risk patients with breast cancer getting genetic testing?

Genetic testing can be a powerful tool for both men and women with breast cancer. This tool can also help identify other family members at risk for disease. But many are not learning about this as an option in their care.

Achieving universal cancer care requires precision and personalized medicine

Achieving universal cancer care requires precision and personalized medicine

In a recent blog, the author emphasizes how important it is that patients “understand the basics of precision and personalized medicine and feel empowered to make decisions regarding how their data will be used for themselves and to save the lives of others.”

A Consortium of Researchers, NSIGHT, tackles big issues for tiny patients

A Consortium of Researchers, NSIGHT, tackles big issues for tiny patients

Ever think about the possibility of genome- scale sequencing in your baby? This publication shares some thoughts about this very real possibility.