The Genetics Home Reference offers easy-to-read summaries of about 1,200 genetic conditions, more than 1,450 genes, all of the human chromosomes, and mitochondrial DNA. New and updated summaries are added regularly. The Genetics Home Reference also strives to provide topical information. See recently added entries to the educational primer, Help Me Understand Genetics, discuss Neanderthal DNA, genome editing, and newborn genomic screening.
Dr Francis Collins, Director of the National Institutes of Health (NIH), describes the All of Us Program in a recent blog. You can choose to be a participant in this research resource of data and biological samples. You can consent to contribute online health data, complete health surveys, and provide electronic health records. In the future physical measurements, blood and urine samples may be requested. If you enroll, you will be an active partner and get your information back which may help you learn more about your health. The Director’s blog also lists video links to information that may help you decide if you want to be one of the million volunteers to help speed medical discoveries.
NHGRI notes, whether you realize it or not, many parts of our daily lives are influenced by genomic information and genomic technologies. Genomics now provides a powerful lens for use in various areas - from medical decisions, to food safety, to ancestry. See the video that describes the celebration and review the 15 ways that genomics has and will continue to transform our world.
We have a number of microbes living on different parts of our bodies. NIH Director, Dr F. Collins provides details about metagenomes gathered from 265 healthy volunteers that indicate diversity as well as similarities of the microorganisms living on and within our bodies.
The Child Enrollment Scientific Vision Working Group of the All of Us Advisory Panel seeks public input on the pediatric research that the All of Us Research Program may be uniquely positioned to enable through the enrollment of children. All responses must be submitted via web form by September 12, 2017, for the working group members to consider during the development of their report.
Genome editing is a tool used in the laboratory setting to make changes to a organism's genetic material. A recent report from the National Academies of Sciences provides a review of the advances in this technology and offers recommendations for safe use of genome editing to improve human health. Yesterday a new Nature publication about the first human embryo gene editing in the US at OHSU stimulates discussion and controversy about the potential risks for future generations.
This targeted treatment study is for children and adolescents (ages 1 to 21) with solid tumors no longer responding to standard treatment or have recurred after treatment. The study matches patients with therapies aimed at molecular abnormalities in their tumors. Enrollment is available at children’s hospitals, university medical centers, and cancer centers across the US that are part of the Children's Oncology Group.
Presenter Katherine Bowman was study director for the recently released report on human genome editing. This webinar reported on the findings and recommendations of the National Academy of Sciences and National Academy of Medicine committee.
Obesity is a global health problem, contributing to premature death and morbidity by increasing a person's risk of developing diabetes, hypertension, heart disease and some cancers. While obesity mostly results from lifestyle and cultural factors, including excess calorie intake and inadequate levels of physical activity, it has a strong genomic component (NHGRI, 2017)
The advent of a powerful gene-editing tool called Crispr-Cas9 allows researchers to snip, insert and delete genetic material of humans with increasing precision. But should we? A new report out differs from perspectives in 2015.